Development of Delta Opioid Peptides as Nonaddicting Analgesics
- 1 January 1991
- journal article
- review article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 8 (1) , 1-8
- https://doi.org/10.1023/a:1015809702296
Abstract
Although much effort has been devoted to opioid research since the identification of enkephalins, understanding of the physiological importance and mechanisms of action of endogenous opioids lags behind understanding of opiate alkaloids such as morphine. In recent years, several novel approaches have been refined with promise for the successful development of the long-awaited nonaddicting analgesics that act at the opioid delta receptor. The present communication reviews these efforts.Keywords
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