Effect of Cortisone upon Local Capillary Permeability

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Abstract
Various products of protein digestion and extracts of normal tissues caused increased capillary permeability when injd. intradermally. This effect was reduced greatly by pre-treatment with cortisone. Local edema and leukocytic infiltration developed at the site of the injns. These effects were more acute in the untreated animals. There was evidence that cortisone inhibited the emigration of leukocytes from within the minute vessels.

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