Sequence and analysis of the rpoB gene of Mycobacterium smegmatis
- 1 September 1995
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 39 (9) , 2164-2166
- https://doi.org/10.1128/aac.39.9.2164
Abstract
The rpoB gene encodes the beta subunit of the DNA-dependent RNA polymerase of bacteria. Mutations in defined areas result in resistance to rifampin. Mycobacterium smegmatis is naturally resistant to rifampin, but analysis of the rpoB gene revealed no identifiable rifampin resistance mutations. Another mechanism of resistance may be present.Keywords
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