Synthesis and properties of hammerhead ribozymes stabilized against nucleases by different 2′-modifications: methoxyethoxy-, fluoro- and amino groups
- 8 July 1997
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 7 (13) , 1791-1796
- https://doi.org/10.1016/s0960-894x(97)00313-2
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Correlation of Activity with Stability of Chemically Modified Ribozymes in Nuclei SuspensionAntisense and Nucleic Acid Drug Development, 1996
- Chemical Modification of Hammerhead RibozymesJournal of Biological Chemistry, 1995
- Ein neuer Zugang zu 2′‐O‐Alkylribonucleosiden und Eigenschaften deren OligonucleotideHelvetica Chimica Acta, 1995
- Synthesis of Uridine Phosphoramidite Analogs: Reagents for Site-Specific Incorporation of Photoreactive Sites into RNA SequencesBioconjugate Chemistry, 1994
- Ribozymes designed to inhibit transformation of NIH3T3 cells by the activated c-Ha-ras geneGene, 1992
- Ribozymes as Anti-HIV-1 Therapeutic Agents: Principles, Applications, and ProblemsAIDS Research and Human Retroviruses, 1992
- Physical Factors Contributing to the Partition Coefficient and Retention Time of 2',3'-Dideoxynucleoside AnaloguesJournal of Pharmaceutical Sciences, 1991
- Sequence requirements of the hammerhead RNA self-cleavage reactionBiochemistry, 1990
- Simple RNA enzymes with new and highly specific endoribonuclease activitiesNature, 1988
- A small catalytic oligoribonucleotideNature, 1987