Mitotic Inhibition of ICR 2A Frog Cells Exposed to 265–313 nm Monochromatic Ultraviolet Wavelengths and Photoreactivating Light
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 45 (1) , 85-91
- https://doi.org/10.1080/09553008414550101
Abstract
Exposure of ICR 2A frog [embryo] cells to 265, 289, 302 or 313 nm UV radiation caused a decrease in the MI [mitotic index] of the irradiated cells in a fluence-dependent fashion. Treatment of cells with PRL [photoreactivating light] immediately after UV-irradiation resulted in a smaller decrease in the MI, demonstrating that pyrimidine dimers played a role in the mitotic inhibition induced by these UV wavelengths. The effect of PRL on 313 nm-irradiated cells was much smaller than for the other wavelengths tested, indicating that non-dimer photoproducts were of importance in the mitotic inhibition induced by this UV wavelength.This publication has 16 references indexed in Scilit:
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