Levamisole therapy in atopic dermatitis: randomized double-blind evaluation

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Abstract
A randomized double-blind study of levamisole hydrochloride therapy in atopic dermatitis was reported. No improvement was noted in any of several assessments, which included patients'' subjective impressions, physicians'' clinical impressions, comparison of clinical extent and severity scores and incidence of cutaneous infections or lessening of serum Ig[immunoglobulin]E levels. Improvement was seen in a majority of cases, whether treatment was with a placebo or an active drug. The need for double-blind techniques for therapeutic trial in the management of patients with atopic dermatitis was emphasized.