Neuromuscular Blockade by Succinylcholine in Children

Abstract
Electromyographywas utilized to study the effects of succinylcholine in children. The effects of 0.3 mg/kg intravenously were inversely related to the age of the patient. During continuous infusion of succinylcholine, the dose required to decrease the compound action potential to 50% of the control was inversely related to the age of the patient. No age relation was observed if 0.5 mg/kg was injected intravenously. The results indicated that the younger children were more resistant to the neuromuscular blockade produced by succinylcholine.

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