PROPERTIES AND CLINICAL-SIGNIFICANCE OF AN ALKALINE PHOSPHATASE-LIPOPROTEIN-X COMPLEX

  • 1 January 1980
    • journal article
    • research article
    • Vol. 26  (5) , 609-612
Abstract
The existence of an alkaline phosphatase-lipoprotein-X complex was demonstrated as an abnormally moving band in the agar-agarose gel alkaline phosphatase pattern of sera from 58 patients in a group of 72 patients whose sera contained lipoprotein-X. The position of the abnormally moving band in the agar-agarose gel alkaline phosphatase pattern and the percentage of alkaline phosphatase activity in the complex in relation to the total serum alkaline phosphatase activity depend on the serum lipoprotein-X concentration. The presence of the complex is a reliable indicator for cholestasis and of limited value in the differentiation between intrahepatic and extrahepatic cholestasis.

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