Double-blind Cross-over Study of Ketoprofen and Ibuprofen in Management of Rheumatoid Arthritis
- 13 October 1973
- Vol. 4 (5884) , 82-84
- https://doi.org/10.1136/bmj.4.5884.82
Abstract
A double-blind cross-over study of ketoprofen (Orudis) 150 mg daily and ibuprofen (Brufen) 1,200 mg daily was carried out in 35 outpatients with rheumatoid arthritis. Results suggest that analgesic and anti-inflammatory activity of ketoprofen is superior to that of ibuprofen. Significantly greater pain relief (P < 0·05) and reduction in joint circumference (P < 0·01) was obtained with ketoprofen than with ibuprofen. Side effects of the drugs were comparable and not serious.Keywords
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