New Strategies in Preparing Organo-Substituted Cyclophosphazenes
- 1 March 1987
- journal article
- research article
- Published by Taylor & Francis in Phosphorus and Sulfur and the Related Elements
- Vol. 30 (1-2) , 519-522
- https://doi.org/10.1080/03086648708080634
Abstract
Nucleophilic addition of a copper-phosphazene anion [(NPCl2)2NPR]2Cu (R = alkyl) to an aldehyde or ketone, followed by acid hydrolysis, leads to the formation of geminal alkyl(hydroxy-alkyl) derivatives in reasonable to high yields. Isocyanato cyclophosphazenes provide another entrance to organo-substituted derivatives, in which (NPCl2)2 NPNH2 NCO appears to be a versatile starting material. Interesting differences are observed between the reactions of (NPCl2)3 with alkali cyanates and silver cyanate in the presence of an alcohol, using acetonitrile as a solvent.Keywords
This publication has 5 references indexed in Scilit:
- Isomer-dependent cytostatic activity of bis(1-aziridinyl)cyclophosphazenesJournal of Medicinal Chemistry, 1986
- New designs and structure activity relationships in antitumoral aziridinyl cyclophospha(thia)zenesPhosphorus and Sulfur and the Related Elements, 1983
- Phosphine-linked phosphazenes as carrier molecules for transition-metal complexesOrganometallics, 1983
- Organofunctional phosphazenes and organofunctional phosphazene polymersJournal of Polymer Science: Polymer Symposia, 1983
- Formation of hydridocyclotriphosphazenes via the reactions of organocopper reagents with halocyclotriphosphazenes. Reaction mechanismJournal of the American Chemical Society, 1979