STUDIES ON THE PREVENTION OF RHEUMATIC FEVER: THE EFFECT OF TIME OF INITIATION OF TREATMENT OF STREPTOCOCCAL INFECTIONS ON THE IMMUNE RESPONSE OF THE HOST 1

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Abstract
Early treatment of streptococcal pharyngitis with penicillin is more effective than delayed therapy in suppression of antistreptolysin antibody formation. Treatment instituted as late as 5 days from onset of symptoms of pharyngitis results in significant antibody suppression.