Effect of Types of Treatment on Development of Antistreptolysin in Patients with Scarlet Fever.

Publisher Website
Google Scholar
Abstract
72% of patients with scarlet fever who received only symptomatic treatment were found to develop a rise in the antistreptolysin titer, the av. increase being 300 U. Of patients treated with conc. human y globulin, 64% experienced an increase in antistrepto-lysin, the av. being 279 U. In 33 patients who received 1,200,000 U. of penicillin over a period of 10 days, only 13% showed an antibody response, and the av. rise in this group was only 189 U. 87% of the penicillin-treated patients exhibited no increase in antistreptolysin. Little correlation could be established between complications and presence or absence of an increase in antistreptolysin except that glomeru-lar nephritis and acute rheumatic fever occurred only in those who showed a rise in titer of this antibody.