LACK OF PHYSIOLOGIC EOSINOPHIL RHYTHM DURING ADVANCED PREGNANCY OF A PATIENT WITH ADDISON'S DISEASE
- 1 July 1954
- journal article
- research article
- Published by Bioscientifica in Acta Endocrinologica
- Vol. 16 (3) , 227-232
- https://doi.org/10.1530/acta.0.0160227
Abstract
Eosinophil counts were made on 27 samples of venous blood withdrawn during a 3 day period from a subject with Addison''s disease, receiving no current replacement therapy. The subject carried a living fetus during the 34th week of pregnancy. Irrespective of experimental regimens and in the absence of obvious immediate ill effects from the discontinuance of therapy, the subject had no eosinophil rhythm of physiologic amplitude. No dogmatic conclusion regarding fetal adrenal physiology can be made, but apparently the 24 hours adrenal cycle observed in humans after the first year of life is absent in utero.Keywords
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