Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2
- 16 January 2009
- journal article
- research article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 378 (3) , 473-477
- https://doi.org/10.1016/j.bbrc.2008.11.048
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- The selectivity of protein kinase inhibitors: a further updateBiochemical Journal, 2007
- LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activityBiochemical Journal, 2007
- Role of Mitochondrial Dysfunction in Parkinson???s DiseaseDrugs & Aging, 2007
- An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic miceProceedings of the National Academy of Sciences, 2006
- Rapid Access to Unexplored Chemical Space by Ligand Scanning around a Ruthenium Center: Discovery of Potent and Selective Protein Kinase InhibitorsJournal of the American Chemical Society, 2005
- Alpha-synuclein and neurodegenerative diseasesNature Reviews Neuroscience, 2001
- Mutation in the α-Synuclein Gene Identified in Families with Parkinson's DiseaseScience, 1997
- Inhibition of protein kinase C μ by various inhibitors. Inhibition from protein kinase c isoenzymesFEBS Letters, 1996
- Differential Biological Effects of K252 Kinase Inhibitors Are Related to Membrane Solubility but Not to PermeabilityJournal of Neurochemistry, 1995
- K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinasesBiochemical and Biophysical Research Communications, 1986