Cathepsin D coexists with renin in the secretory granules of juxtaglomerular epithelioid cells
- 1 January 1986
- journal article
- research article
- Published by Springer Nature in Histochemistry and Cell Biology
- Vol. 84 (1) , 19-22
- https://doi.org/10.1007/bf00493415
Abstract
Mature juxtaglomerular epithelioid cell secretory granules of the rat exhibit both renin-and cathepsin D-like immunoreactivity. On the basis of the coexistence with renin at a pH which, according to previous experiments, is probably in the range of that in lysosomes, cathepsin D is suggested to be involved in the regulation of the granular renin stores available for secretion.Keywords
This publication has 18 references indexed in Scilit:
- Immunocytochemical localization of cathepsin D in lysosomes of cortical collecting tubule cells of the rat kidney.Journal of Histochemistry & Cytochemistry, 1985
- Are the renin-containing granules of juxtaglomerular epithelioid cells modified lysosomes?Cell and tissue research, 1985
- Coexistence of renin and cathepsin B in epithelioid cell secretory granulesHistochemistry and Cell Biology, 1985
- A simple post-embedding system for the rapid demonstration of tissue antigens under the electron microscopeJournal of Molecular Histology, 1983
- INTRACELLULAR PROTEOLYTIC MECHANISMS IN THE BIOSYNTHESIS OF HORMONES AND PEPTIDE NEUROTRANSMITTERSPublished by Elsevier ,1983
- Degradation of canine cardiac myosin and actin by cathepsin D isolated from homologous tissueCardiovascular Research, 1979
- Histochemistry of lysosomal enzymes in juxtaglomerular cellsCellular and Molecular Life Sciences, 1969
- The fine structural localization of acid phosphatase in the prolactin cell of the teleost pituitary following the stimulation and inhibition of secretory activityTissue and Cell, 1969
- LYSOSOME FUNCTION IN THE REGULATION OF THE SECRETORY PROCESS IN CELLS OF THE ANTERIOR PITUITARY GLANDThe Journal of cell biology, 1966
- Lysosomal Nature of Juxtaglomerular GranulesScience, 1966