Magnetic resonance imaging in pre-senile dementia of the Alzheimer-type, multi-infarct dementia and Korsakoff's syndrome

1 May 1988

journal article
research article
Published by Cambridge University Press (CUP) in Psychological Medicine

Vol. 18 (2) , 319-329
https://doi.org/10.1017/s0033291700007868

Abstract

Magnetic resonance imaging T₁ values in Alzheimer's disease (ATD) were similar to age-matched controls although frontal T₁ values tended to increase intraindividually with progression of the dementia. T₁ values were raised, in both cortical grey and white matter, in Korsakoff's syndrome and multi-infarct dementia. T₁ values appear of little value in studying the neuropathological changes in ATD in relationship to the neuropsychological deficits, but can assist in the differential diagnosis of pre-senile dementia.

Keywords

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