INCREASED β-2 MICROGLOBULINURIA IN HUMAN IMMUNODEFICIENCY VIRUS-1-INFECTED CHILDREN AND ADOLESCENTS TREATED WITH TENOFOVIR
- 1 October 2007
- journal article
- other
- Published by Wolters Kluwer Health in The Pediatric Infectious Disease Journal
- Vol. 26 (10) , 949-951
- https://doi.org/10.1097/inf.0b013e3181256570
Abstract
A single-center cross sectional evaluation of β-2 microglobinuria as a marker of proximal renal tubule damage in 92 HIV-infected children showed that tenofovir treatment was significantly associated with very high abnormal values. In view of the very long duration of treatments for HIV infection, their possible consequences for the child's growing body should be carefully evaluated.Keywords
This publication has 10 references indexed in Scilit:
- Association betweenABCC2Gene Haplotypes and Tenofovir‐Induced Proximal TubulopathyThe Journal of Infectious Diseases, 2006
- Tenofovir Disoproxil Fumarate and an Optimized Background Regimen of Antiretroviral Agents as Salvage Therapy: Impact on Bone Mineral Density in HIV-Infected ChildrenPublished by American Academy of Pediatrics (AAP) ,2006
- Urinaryβ2-Microglobulin as a Possible Sensitive Marker for Renal Injury Caused by Tenofovir Disoproxil FumarateAIDS Research and Human Retroviruses, 2006
- Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavirPediatric Nephrology, 2006
- HIV-Associated Renal Diseases and Highly Active Antiretroviral Therapy--Induced NephropathyClinical Infectious Diseases, 2006
- Exploring Mitochondrial Nephrotoxicity as a Potential Mechanism of Kidney Dysfunction among HIV-Infected Patients on Highly Active Antiretroviral TherapyAntiviral Therapy, 2006
- A 12-Month Treatment With Tenofovir Does Not Impair Bone Mineral Accrual in HIV-Infected ChildrenJAIDS Journal of Acquired Immune Deficiency Syndromes, 2005
- Renal tubular toxicity associated with tenofovir assessed using urine-beta 2 microglobulin, percentage of tubular reabsorption of phosphate and alkaline phosphatase levelsAIDS, 2005
- Tenofovir Disoproxil FumarateDrugs, 2005
- HUMAN RENAL ORGANIC ANION TRANSPORTER 1 (hOAT1) AND ITS ROLE IN THE NEPHROTOXICITY OF ANTIVIRAL NUCLEOTIDE ANALOGSNucleosides, Nucleotides and Nucleic Acids, 2001