Adhesion Molecules

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Abstract
This chapter will focus on the role of adhesion molecules in ovarian carcinoma. Specifically, we will focus on the interactions that occur between ovarian carcinoma cells and peritoneal mesothelial cells as well as their associated extracellular matrices (ECM). Cell-cell and cell-ECM interactions play an important role in cancer cell adhesion, migration, invasion, growth, survival, and programmed cell death (apoptosis). By better understanding the molecules involved in ovarian carcinoma cell adhesion, it may be possible to identify reagents that can prevent the dissemination of ovarian carcinoma in vivo.