Age and duration of illness as predictors of ventricular brain ratio (VBR) size in chronic schizophrenic patients

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Abstract
The CT scans of 18 chronic schizophrenic patients and 17 controls were evaluted for Ventricular Brain Ratio (VBR) size. A trend for the patient group to have larger VBR than controls was present but did not reach statistical significance at the 5% level. Age was found to be an important correlate of VBR within the patient group but not among controls. In a stepwise multiple‐regression model age, among other independent variables, can account for 47% of VBR variance in schizophrenic patients. Linear regression analysis did not reveal significant association between VBR and age in control subjects.