The effect of ageing on human lymphocyte subsets: comparison of males and females
Open Access
- 16 March 2010
- journal article
- Published by Springer Nature in Immunity & Ageing
- Vol. 7 (1) , 4
- https://doi.org/10.1186/1742-4933-7-4
Abstract
There is reported to be a decline in immune function and an alteration in the frequency of circulating lymphocytes with advancing age. There are also differences in ageing and lifespan between males and females. We performed this study to see if there were differences between males and females in the frequency of the different lymphocyte subsets with age.Keywords
This publication has 72 references indexed in Scilit:
- Age-associated declines in immune system development and function: causes, consequences, and reversalCurrent Opinion in Immunology, 2009
- Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donorsImmunity & Ageing, 2009
- NK cells in the CD19− B220+ bone marrow fraction are increased in senescence and reduce E2A and surrogate light chain proteins in B cell precursorsMechanisms of Ageing and Development, 2009
- Immunosenescence: what does it mean to health outcomes in older adults?Published by Elsevier ,2009
- The genetics of gender and life spanJournal of Biology, 2009
- On sexual dimorphism in immune functionPhilosophical Transactions Of The Royal Society B-Biological Sciences, 2008
- Gene expression changes in long‐term culture of T‐cell clones: genomic effects of chronic antigenic stress in aging and immunosenescenceAging Cell, 2007
- Immunosenescence of ageingThe Journal of Pathology, 2007
- Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humansHuman Immunology, 2005
- Changes with ageing in several leukocyte functions of male and female ratsBiogerontology, 2004