Radioimmunoassay of thyrotropin and thyroxine in dried blood by use of Staphylococcus aureus containing "protein A.".
- 1 July 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 26 (8) , 1140-1142
- https://doi.org/10.1093/clinchem/26.8.1140
Abstract
We report the use of Staphylococcus aureus rich in protein A as an immunoadsorbent in the radioimmunoassay of thyrotropin and thyroxine in blood collected from newborn infants and dried on filter paper. The procedures for thyrotropin and thyroxine, which differ mainly with respect to concentration and volume of the Staphylococcus aureus suspension, are reliable, rapid, and technically simple. The ease of this method, coupled with its dependability, offers certain advantages over some of the commonly used techniques of separation, and therefore it provides a unique approach to measurement of these analytes in laboratory screening programs for neonatal hypothyroidism.This publication has 4 references indexed in Scilit:
- DRIED STAPHYLOCOCCUS AUREUS AS A RAPID IMMUNOLOGICAL SEPARATING AGENT IN RADIOIMMUNOASSAYSJournal of Clinical Endocrinology & Metabolism, 1979
- Screening for congenital hypothyroidism. Results in the newborn population of New EnglandJAMA, 1978
- Improved thyroxine radioimmunoassay, for filter paper discs saturated with dried blood.Clinical Chemistry, 1976
- IMMUNOASSAY OF HUMAN TSH USING DRIED BLOOD SAMPLES1Journal of Clinical Endocrinology & Metabolism, 1976