Regulation of a Hybrid Gene by Glucose and Temperature in Hamster Fibroblasts
- 12 October 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 226 (4671) , 187-190
- https://doi.org/10.1126/science.6484570
Abstract
A novel eukaryotic hybrid gene has been constructed from the 5' sequence of a rat gene and the bacterial neomycin-resistance gene. After transfection into hamster fibroblasts, the neo transcripts can be induced to high levels by the absence of glucose. Furthermore, this hybrid gene can be regulated by temperature when it is introduced into a temperature-sensitive mutant cell line.This publication has 22 references indexed in Scilit:
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