THE NUTRITIVE SIGNIFICANCE OF THE AMINO ACIDS

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Abstract
The author reviews the evidence for placing lysine, tryptophane, histidine, phenylalanine, leucine, isoleucine, threonine, methionine, valine, and arginine on the list of amino acids which can not be synthesized by the mammalian organism, out of the materials ordinarily available, at a speed sufficient for normal growth, though arginine can be synthesized in small amts. Glycine, alanine, serine, norleucine, aspartic acid, glutamic acid, hydroxyglutamic acid, proline, hydroxy-proline, citrulline, tyrosine, and cystine can be omitted from a dietary ration without entailing a diminished growth rate. Of the 10 indispensable amino acids, both the d- and 1-forms of tryptophane, histidine, phenylalanine, and methionine promote growth, whereas the natural form of valine, leucine, isoleucine, lysine, and threonine can not be replaced by the d-form. (Arginine has not been tested in this respect.).

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