Ten year follow up of microprolactinoma treated by transsphenoidal surgery

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Abstract
We tried to obtain information about patients who were not currently being followed up in Glasgow by contacting their general practitioner, referring specialist, and the patients themselves, achieving a 10 year follow up in 45 of the 61 patients (74%). We defined cure of hyperprolactinaemia as a plasma prolactin concentration within the reference range (60-360 mU/l), operative failure as a persistently raised prolactin concentration, and recurrence as a sustained increase in prolactin concentration after a normal value had been achieved. In four patients prolactin concentration was variably raised during follow up.