MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula
Top Cited Papers
- 15 November 2006
- journal article
- Published by Cold Spring Harbor Laboratory in Genes & Development
- Vol. 20 (22) , 3084-3088
- https://doi.org/10.1101/gad.402806
Abstract
In the model legume Medicago truncatula, we identified a new transcription factor of the CCAAT-binding family, MtHAP2-1, for which RNA interference (RNAi) and in situ hybridization experiments indicate a key role during nodule development, possibly by controlling nodule meristem function. We could also show that MtHAP2-1 is regulated by microRNA169, whose overexpression leads to the same nodule developmental block as MtHAP2-1 RNAi constructs. The complementary expression pattern of miR169 and MtHAP2-1 and the phenotype of miR169-resistant MtHAP2-1 nodules strongly suggest, in addition, that the miR169-mediated restriction of MtHAP2-1 expression to the nodule meristematic zone is essential for the differentiation of nodule cells.Keywords
This publication has 28 references indexed in Scilit:
- Mutations in the MicroRNA Complementarity Site of the INCURVATA4 Gene Perturb Meristem Function and Adaxialize Lateral Organs in ArabidopsisPlant Physiology, 2006
- MtENOD11 Gene Activation During Rhizobial Infection and Mycorrhizal Arbuscule Development Requires a Common AT-Rich-Containing Regulatory SequenceMolecular Plant-Microbe Interactions®, 2005
- Computational detection of microRNAs targeting transcription factor genes in ArabidopsisthalianaComputational Biology and Chemistry, 2005
- LysM Domain Receptor Kinases Regulating Rhizobial Nod Factor-Induced InfectionScience, 2003
- LEAFY COTYLEDON1-LIKE Defines a Class of Regulators Essential for Embryo DevelopmentPlant Cell, 2002
- Ternary Complex Formation between MADS-box Transcription Factors and the Histone Fold Protein NF-YBJournal of Biological Chemistry, 2002
- Medicago truncatula ENOD11: A Novel RPRP-Encoding Early Nodulin Gene Expressed During Mycorrhization in Arbuscule-Containing CellsMolecular Plant-Microbe Interactions®, 2001
- MtENOD20, a Nod Factor-Inducible Molecular Marker for Root Cortical Cell ActivationMolecular Plant-Microbe Interactions®, 1999
- Rhizobium meliloti lipooligosaccharide nodulation factors: different structural requirements for bacterial entry into target root hair cells and induction of plant symbiotic developmental responses.Plant Cell, 1994
- Rhizobium meliloti Nod factors elicit cell‐specific transcription of the ENOD12 gene in transgenic alfalfaThe Plant Journal, 1994