CARDIORESPIRATORY EFFECTS OF INCREASED AIRWAY PRESSURE DURING CONTROLLED AND SPONTANEOUS BREATHING AFTER CARDIAC SURGERY

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Abstract
The cardiorespiratory effects of intermittent positive pressure ventilation with zero end-expiratory pressure (IPPV), continuous positive airway pressure breathing (CPAP) and spontaneous breathing (SR) were studied in 11 patients 3-20 h after open-heart surgery. The transition from IPPV to CPAP resulted in a significant reduction in tidal volume and significant increases in respiratory frequency, PaCO2 [arterial tension of CO2], O2 transport and mean arterial pressure, but there were no significant changes in cardiac output or PaO2. There was no significant differences in any of the measurements between CPAP and SR.