Maternal vegan diet causing a serious infantile neurological disorder due to vitamin B12 deficiency
- 1 January 1991
- journal article
- case report
- Published by Springer Nature in European Journal of Pediatrics
- Vol. 150 (3) , 205-208
- https://doi.org/10.1007/bf01963568
Abstract
We present a 9-month-old exclusively breastfed baby of a strict vegetarian mother who had excluded all animal proteins from her diet. The patient's symptoms included dystrophy, weakness, muscular atrophy, loss of tendon reflexes, psychomotor regression and haematological abnormalities. Biochemical investigations revealed severe methylmalonic aciduria and homocystinuria in the patient, slight methylmalonic aciduria in the mother and low concentrations of serum vitamin B12 in both patient and mother.Keywords
This publication has 17 references indexed in Scilit:
- Nutritional Vitamin B12Deficiency in Infancy: Three Case Reports and a Review of the LiteraturePediatric Hematology and Oncology, 1989
- Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry.Journal of Clinical Investigation, 1988
- Vitamin B12 and brain developmentEuropean Journal of Pediatrics, 1987
- Megaloblastic anaemia in one of monozygous twins breast fed by their vegetarian motherEuropean Journal of Pediatrics, 1986
- Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry.Journal of Clinical Investigation, 1986
- THE METHYL FOLATE TRAP A physiological response in man to prevent methyl group deficiency in kwashiorkor (methionine deficiency) and an explanation for folic-acid-induced exacerbation of subacute combined degeneration in pernicious anaemiaThe Lancet, 1981
- A Syndrome of Methylmalonic Aciduria, Homocystinuria, Megaloblastic Anemia and Neurologic Abnormalities in a Vitamin B12-Deficient Breast-Fed Infant of a Strict VegetarianNew England Journal of Medicine, 1978
- Fatty acid composition of myelin isolated from the brain of a patient with cellular deficiency of co-enzyme forms of vitamin B12Journal of the Neurological Sciences, 1977
- Nutritional vitamin B12 deficiency in an infantThe Journal of Pediatrics, 1969
- Vitamin-B12 Deficiency in Pregnancy and the PuerperiumBMJ, 1962