gamma-Glutamylamine cyclotransferase: specificity toward epsilon-(L-gamma-glutamyl)-L-lysine and related compounds.
- 1 August 1980
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 77 (8) , 4564-4568
- https://doi.org/10.1073/pnas.77.8.4564
Abstract
.gamma.-Glutamylamine cyclotransferase, an enzyme that catalyzes the conversion of L-.gamma.-glutamylamines to free amines and 5-oxo-L-proline, was found in rabbit kidney and in various other tissues. The specificity of this enzyme indicates that it functions in the metabolism of products of transglutaminase action; among its substrates are .epsilon.-(L-.gamma.-glutamyl)-L-lysine, a derivative of this peptide in which the .alpha.-amino and carboxyl groups of the lysine moiety are blocked, and L-.gamma.-glutamylpolyamine derivatives.This publication has 20 references indexed in Scilit:
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