PRODUCTION OF PORTER-SILBER REACTIVE MATERIAL BY HUMAN PLACENTA INCUBATEDIN VITRO1

Abstract
Eleven term placentas were incubated in Krebs-Ringer solution and maternal serum from the same patient. Estimations of free 17-hydroxy-corticosteroid by the Nelson and Samuels method were made of the medium and the placental tissue before and after incubation. An increase of 17-hydroxycorticosteroid was demonstrated in the medium after incubation, without a significant loss from the placental homogenates.

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