THE EFFECT OF GLUCOSE ON THE CIRCULATING EOSINOPHILS

Abstract
Glucose causes a decrease in the circulating eosinophils, occurring in 2 phases; the 2st decrease taking place 30 min. after the admn. of glucose and coinciding with the highest level of blood sugar, the 2d decrease taking place after the blood sugar has fallen to below the initial level (about 2 hrs. after the admn. of glucose.) This 2d decrease was more marked in diabetics and less marked in Addisonians than in normals. It is not the elevation of the blood sugar level but rather the decrease to the initial level or below, that stimulates the pituitary-adrenal system.