Biodegradable Nanoparticles Containing Doxorubicin-PLGA Conjugate for Sustained Release
- 1 January 1999
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 16 (7) , 1114-1118
- https://doi.org/10.1023/a:1018908421434
Abstract
Purpose. Doxorubicin was chemically conjugated to a terminal end group of poly(D,L-lactic-co-glycolic acid) [PLGA] and the doxorubicin-PLGA conjugate was formulated into nanoparticles to sustain the...Keywords
This publication has 11 references indexed in Scilit:
- HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell lineJournal of Controlled Release, 1998
- Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fateJournal of Controlled Release, 1998
- Pharmaceutical and biological properties of doxorubicin encapsulated in liposomes (L‐ADM): The effect of repeated administration on the systemic phagocytic activity and pharmacokineticsBiopharmaceutics & Drug Disposition, 1995
- Prolongation of the Circulation Time of Doxorubicin Encapsulated in Liposomes Containing a Polyethylene Glycol-Derivatized Phospholipid: Pharmacokinetic Studies in Rodents and DogsPharmaceutical Research, 1993
- Preparation of micelle-forming polymer-drug conjugatesBioconjugate Chemistry, 1992
- Drug-polymer conjugatesAnti-Cancer Drugs, 1992
- Passive tumor targeting of soluble macromolecules and drug conjugates.1992
- Tumoritropic and lymphotropic principles of macromolecular drugs.1989
- Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumor protein neocarzinostatin: pronounced improvements in pharmacological propertiesJournal of Medicinal Chemistry, 1985
- Drug-carrier Property of Albumin Microspheres in Chemotherapy. V. Antitumor Effect of Microsphere-entrapped Adriamycin on Liver Metastasis of AH 7974 Cells in RatsCHEMICAL & PHARMACEUTICAL BULLETIN, 1981