Prolongation of the Circulation Time of Doxorubicin Encapsulated in Liposomes Containing a Polyethylene Glycol-Derivatized Phospholipid: Pharmacokinetic Studies in Rodents and Dogs
- 1 January 1993
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 10 (5) , 703-708
- https://doi.org/10.1023/a:1018907715905
Abstract
The pharmacokinetics of doxorubicin (DOX) encapsulated in liposomes containing polyethylene glycol-derivatized distearoylphosphatidylethanolamine (PEG/DSPE) were investigated in rodents and dogs. The...Keywords
This publication has 25 references indexed in Scilit:
- Pharmacokinetic and imaging studies in patients receiving a formulation of liposome-associated adriamycinBritish Journal of Cancer, 1991
- Vascular and interstitial barriers to delivery of therapeutic agents in tumorsCancer and Metastasis Reviews, 1990
- EFFECT OF LIPOSOME COMPOSITION AND OTHER FACTORS ON THE TARGETING OF LIPOSOMES TO EXPERIMENTAL-TUMORS - BIODISTRIBUTION AND IMAGING STUDIES1990
- Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomesFEBS Letters, 1990
- Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.Proceedings of the National Academy of Sciences, 1988
- Stability of anthracycline antitumour agents in infusion fluids.1985
- PLASMA PHARMACOKINETICS OF ADRIAMYCIN AND ADRIAMYCINOL - IMPLICATIONS FOR THE DESIGN OF INVITRO EXPERIMENTS AND TREATMENT PROTOCOLS1983
- FACILE AND DEFINITIVE DETERMINATION OF HUMAN ADRIAMYCIN AND DAUNORUBICIN METABOLITES BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY1980
- Statistical moments in pharmacokineticsJournal of Pharmacokinetics and Biopharmaceutics, 1978
- Adriamycin metabolism in man. Evidence from urinary metabolites.1976