Empty sella and rhinorrhea

Abstract
The association of an empty sella with rhinorrhea is an unusual finding. Of 29 cases of empty sella 8 underwent surgery for rhinorrhea. None of the patients showed clinical evidence of increased intracranial pressure or hydrocephalus. Seven were cases of primary empty sella, the 8th was an acromegalic patient who had received radiotherapy 4 yr before. The others showed no clinical signs of a previous tumor. In the surgical treatment of these patients, both the transfrontal and transsphenoidal approaches were used. In spite of generally accepted good results following surgical closure of this type of fistula, 4 patients needed more than 1 operation. The fistula closed in only 3 of them; in the last patient rhinorrhea persisted after 3 operations.

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