Total chemical synthesis of enzymes
- 1 September 2003
- journal article
- other
- Published by Wiley in Journal of Peptide Science
- Vol. 9 (9) , 574-593
- https://doi.org/10.1002/psc.475
Abstract
The total synthesis, at will, of a wide variety of protein and enzyme molecules is made feasible by modern chemical ligation methods. As Emil Fischer intuitively understood, synthetic access to the enzyme molecule enables the power of chemical science to be applied to elucidating the molecular basis of catalytic function in unprecedented detail. Copyright © 2003 European Peptide Society and John Wiley & Sons, Ltd.Keywords
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