Prevalence of thyroid disorder in Down syndrome
- 1 September 1978
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 14 (3) , 154-158
- https://doi.org/10.1111/j.1399-0004.1978.tb02121.x
Abstract
Thyroid function was studied in 121 patients between 13-48 yr old with proven Down syndrome. Chemically, hypothyroidism was found in 17% and hyperthyroidism in 2.5% of the patients; 18% of patients had goiter. Thyroid antibodies were detected in 33% of subjects studied. The abnormal findings were almost equally distributed between the sexes above 20 yr of age; however, females had significantly more thyroid disease than males in the younger age group.Keywords
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