Effects of Protein Depletion and Inanition on Serum Glycoprotein Concentrations in the Rat.

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Abstract
The effects of protein depletion and inanition on serum concentrations of total glycoproteln, seromucoid, albumin polysaccharide, globulin polysaccharide, total protein, albumin, and globulin and on hemoglobin and hematocrit values of blood were investigated in adult, male Sprague-Dawley rats. Significant decreases were observed in all serum fractions except the albumin. The response of the protein-bound carbohydrates was similar to that of the proteins. Marked hemoconcentration occurred in the fasted group. The results are not in agreement with the hypothesis that tissue degradation is responsible for increased serum glycoprotein concentrations.