A general QSAR for dihydrofolate reductase inhibition by 2,4-diaminotriazines based upon molecular shape analysis
- 1 January 1981
- journal article
- research article
- Published by Elsevier in Archives of Biochemistry and Biophysics
- Vol. 206 (1) , 153-163
- https://doi.org/10.1016/0003-9861(81)90076-x
Abstract
No abstract availableThis publication has 13 references indexed in Scilit:
- Dihydrofolate reductase inhibition by 2,4-diaminotriazines: A structure-activity studyArchives of Biochemistry and Biophysics, 1979
- Molecular mechanics and the camseq processorComputers & Chemistry, 1977
- Dihydrofolate Reductase: X-ray Structure of the Binary Complex with MethotrexateScience, 1977
- Quantitative structure-activity relations. 7. The bilinear model, a new model for nonlinear dependence of biological activity on hydrophobic characterJournal of Medicinal Chemistry, 1977
- Dihydrofolate reductase from a methotrexate-resistant Escherichia coli: Proton magnetic resonance studies of complexes with folate and methotrexateBiochemical and Biophysical Research Communications, 1975
- Correlation analysis. Its application to the structure-activity relation of triazines inhibiting dihydrofolate reductaseJournal of the American Chemical Society, 1975
- Nuclear magnetic resonance studies of the binding of substrate analogs and coenzyme to dihydrofolate reductase from Lactobacillus caseiBiochemistry, 1974
- Dihydrofolate reductases of Escherichia coli and bacteriophage T4. Spectrofluorometric studyBiochemistry, 1973
- Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coliBiochemistry, 1972
- Circular dichroic studies of the interaction of dihydrofolate reductase with substrates, coenzymes, and inhibitorsBiochemistry, 1972