Anatomy of Vulvar Skin with Emphasis on the Pilosebaceous Unit and Subcutaneous Fat

Abstract
The intradermal depth of the pilosebaceous units of the vulvar skin was evaluated by light microscopy with respect to their geographical distribution in 305 histologic sections from autopsy cases. The mean hair follicle extension was 1.2 mm (SD = 0.53), with 99.5% of all hair follcles extending no deeper than 2.6 mm into the dermis. The mean depth of sebaceous glands throughout the vulvar skin was 0.64 mm (SD = 0.24), with 99.5% of all sebaceous glands extending no deeper than 1.30 mm into the dermis. The mean depth of dermis-subcutaneous fat junction was 1.2 mm (SD = 0.39), with 95% of all measurements being 0.56 mm or more below the epidermal surface. The results provide baseline data for the appropriate treatment depth of intraepithelial neoplasia with possible extension into the pilosebaceous units of the vulvar skin and for the preservation of the latter''s physiologic functions, particularly when using the CO2 laser vaporization technqiue.

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