PAGETOID RETICULOSIS - FURTHER CASE-REPORT WITH A REVIEW OF THE LITERATURE

Google Scholar
  • 1 January 1979
    • journal article
    • research article
    • Vol. 59  (85) , 11-21
Abstract
A further [human] case of pagetoid reticulosis (PR) was studied and the findings were compared with 18 previous case reports. There seem to be 2 variants: the generalized type (Ketron-Goodman) with disseminated lesions and a poor prognosis; and the localized type (Woringer-Kolopp), with a single lesion usually located on the extremities with a good prognosis (if the lesion can be totally cleared by excision or high dose radiation). The basic criterion of diagnosis is a very strong cellular infiltrate within the epidermis, but usually weak in the upper dermis. The etiology of PR remains unclear. In some cases a T[thymus-derived]-cell lymphoma seems a likely interpretation. In others, epidermal infiltrating cells are not typically lymphoid, but remain morphologically unclassifiable.