Secondary hyperalgesia persists in capsaicin desensitized skin
- 1 February 2000
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Pain
- Vol. 84 (2) , 141-149
- https://doi.org/10.1016/s0304-3959(99)00194-3
Abstract
Several lines of evidence suggest that secondary hyperalgesia to punctate mechanical stimuli arises from central sensitization to the input from primary afferent nociceptors. Conventional C-fiber nociceptors respond to heat stimuli and yet heat hyperalgesia is absent in the region of secondaKeywords
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