IMMUNOFLUORESCENT STUDIES ON CANDIDA-ALBICANS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 25  (4) , 265-268
Abstract
The indirect immunofluorescent titers of C. albicans 0656 CBS hyperimmune rabbit serum were investigated against C. albicans antigens [Ag] prepared from strains originating from mucous membranes of healthy persons and patients with thrush. Using pathogenic strains as Ag, a definitely strong fluorescent reaction was obtained with hyperimmune rabbit serum in a dilution of 1:2500. In the case of apathogenic strains, the fluorescent reaction was very weak or negative in a dilution of 1:2000. Absorption studies seemed to reveal a difference in reactivity between pathogenic and apathogenic strains. Hyperimmune rabbit serum absorbed with apathogenic C. albicans strains showed a positive fluorescent reaction only with pathogenic ones as Ag. In the opposite case, a negative reaction was obtained.

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