PARTIAL LIPODYSTROPHY AND CHRONIC HYPOCOMPLEMENTEMIC GLOMERULONEPHRITIS

Abstract
In partial lipodystrophy serious renal disease is common and often has the appearance of chronic hypocomplementemic glomerulonephritis. In this case report a young woman with typical clinical history is described. Low serum levels for C3 were not affected by long‐time immunosuppression, nor was the presence of C3NeF. The degree of renal insufficiency exerted no influence on C3. Transplantation resulted in normalization of C3 and disappearance of C3NeF, persisting even in terminal graft failure.