Myocardial blood flow distribution in miniature pigs during exercise
- 1 July 1977
- journal article
- editorial
- Published by Springer Nature in Basic Research in Cardiology
- Vol. 72 (4) , 326-331
- https://doi.org/10.1007/bf02023592
Abstract
Total and regional myocardial blood flow was measured in miniature pigs at rest and during two levels of treadmill exercise, including maximal exercise. Exercise increased the myocardial blood flow in a linear manner with heart rate (r=0.87). At rest the endocardial/epicardial blood flow ratio was significantly greater than unity with flow favoring the endocardium. Exercise failed to appreciably alter the distribution of coronary blood flow. Thus the myocardium was capable of further dilatation and perfusion of blood without compromising endocardial flow even during the most severe level of exercise when maximal heart rates were attained. Gesamt- und Teildurchblutung des Herzmuskels von Miniaturschweinen wurde im Ruhezustand und bei zwei Stufen von Laufbandbelastung einschließlich Höchstleistungen gemessen. Körperliches Training erhöhte die Herzdurchblutung proportional zur Herzfrequenz. Im Ruhezustand war das Verhältnis zwischen endo- und epikardialer Durchblutung bedeutend größer als 1,0. Laufbandbelastung hatte keinen Einfluß auf die Verteilung der Koronardurchblutung. Selbst während sehr schwerer körperlicher Arbeit und bei sehr hoher Belastung des Herzens war die Durchblutung des Myokards adäquat. Die Koronarreserve war kein limitierender Faktor der Herzleistung.This publication has 11 references indexed in Scilit:
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