Effect of sialoadenectomy on the carriage of Candida albicans in the mouths of rats
- 1 March 1993
- journal article
- Published by Wiley in Journal of Oral Pathology & Medicine
- Vol. 22 (3) , 138-140
- https://doi.org/10.1111/j.1600-0714.1993.tb01045.x
Abstract
Xerostomia provoked in rats by surgical removal of the major salivary glands significantly increased oral carriage of Candida albicans. Five weeks after 3 oral inoculations of 108 CFU, C. albicans were found in the mouths in 50% of normal animals but after 8 weeks in none. In xerostomic rats, 100% had oral C. albicans after 5 weeks and after 18 weeks, 66.6% still harboured yeasts. Over the whole experimental period the amount of C. albicans was greater in the mouths of sialoadenectomized than in normal rats.Keywords
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