Acquired, Transient Factor X (Stuart Factor) Deficiency in a Patient with Mycoplasma Pneumonial Infection

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Abstract
A case of severe hemorrhagic diathesis due to acquired deficiency of factor [F] X (immunologically and in procoagulant activity) was presented. Clinical and serological features of this case indicated mycoplasma pneumonial infection. FX in the peripheral blood did not appear to be influenced by administration of vitamin K, prothrombin-complex concentrate, fresh plasma or fresh whole blood. Circulating inhibitors of blood coagulation were absent and systemic amyloidosis could not be demonstrated. After 20 days FX spontaneously returned to normal. In view of the absence of other known causes of FX deficiency, a possible relationship with mycoplasma pneumonial infection was suggested.