A study of asymmetric protonation with chiral β-hydroxy sulfoxides. Asymmetric synthesis of (–)-epibatidine
- 1 January 1997
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 19,p. 1857-1858
- https://doi.org/10.1039/a704779g
Abstract
The asymmetric synthesis of (–)-epibatidine 1, employing as the key step the asymmetric protonation of the achiral lithum enolate of cyclohexanone derivative 5 with chiral β-hydroxy sulfoxide 3b, is described.Keywords
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