Serum Elastase Inhibitor Deficiency and α 1 -Antitrypsin Deficiency in Patients with Obstructive Emphysema
- 15 August 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 165 (3894) , 709-711
- https://doi.org/10.1126/science.165.3894.709
Abstract
A decreased inhibition of pancreatic elastase has been detected in the serums of six patients with α1-antitrypsin deficiency. Five have severe clinical and physiological pulmonary emphysema. This observation extends the defect of inhibition by serum to a second, biologically active proteolytic enzyme in this form of familial emphysema.Keywords
This publication has 11 references indexed in Scilit:
- Alfa-1-antitrypsin deficiency. A family studyPublished by American Medical Association (AMA) ,1968
- Hereditary Alpha1-Antitrypsin DeficiencyNew England Journal of Medicine, 1968
- A Possible Experimental Approach to the Association of Hereditary 1-Antitrypsin Deficiency and Pulmonary Emphysema.Experimental Biology and Medicine, 1966
- On the Treatment of TetanusActa Medica Scandinavica, 1965
- Pulmonary Emphysema and Alpha1‐Antitrypsin DeficiencyActa Medica Scandinavica, 1964
- The Electrophoretic α;1-Globulin Pattern of Serum in α;1-Antitrypsin DeficiencyScandinavian Journal of Clinical and Laboratory Investigation, 1963
- Microbial Elastases. A Comparative Study.Experimental Biology and Medicine, 1962
- An improved test for the quantitative determination of trypsin, trypsin-like enzymes, and enzyme inhibitorsAnalytical Biochemistry, 1961
- Serum Elastase Inhibitor. Levels in Animal and Human Sera, including Selected Disease States.Experimental Biology and Medicine, 1959
- Comparative Effects of Anesthetic Agents on Incidence of Ventricular Fibrillation During HypothermiaExperimental Biology and Medicine, 1955