Recurrent Epididymitis in Sarcoidosis

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Abstract
A patient with sarcoidosis of the epididymides who had experienced episodes of acute epididymitis every 2 weeks for 12 years is presented. Treatment with corticosteroids produced a remission lasting fifteen months. The success of prednisone alone in achieving this remission and the extensive hyalinization of the epididymal granulomata observed after corticosteroid therapy strongly suggest that the improvement was primarily due to the specific sclerosing and hyalinizing effect of prednisone on sarcoid tissue. Unlike sarcoidosis affecting other genital organs, epididymal sarcoidosis is usually diagnosed after the onset of fairly uniform clinical manifestations. The most frequent findings consist of unilateral, asymptomatic, nodular or diffuse enlargement. Although numerous diseases can elicit a reaction in the epididymis indistinguishable from that of sarcoidosis, tuberculosis is the most common cause of the non-caseating epithelioid granuloma of the epididymis.

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