• 1 January 1966
    • journal article
    • research article
    • Vol. 30  (8) , 233-+
Abstract
The protective effect of orally administered immune (Escherichia coli 08 :K. :H21) serum was demonstrated in experimentally infected gnotobiotic pigs. The temporary protective effect of the immune serum and the correlation of protection with in vitro antibody determinations were discussed. The results indicated that the protective action of the immune serum is apparently not dependent upon the complement-antibody bactericidal system. The most plausible mechanism of action may be of the immune serum was the inactivation of endo-toxin in the lumen of the intestine.

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