Histopathology of experimental systemic candidosis in guinea-pigs
- 1 January 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 22 (6) , 455-469
- https://doi.org/10.1080/00362178485380731
Abstract
Unpretreated Albino guinea-pigs were infected intravenously with Candida albicans. Cutaneous candidosis with (pseudo-) hyphal outgrowth in the hair shafts and in the keratinized layers of the epidermis developed as a consequence of systemic dissemination. The spread of the infection was followed by cultures and by gross- and micropathological study of various organs of different animals during a follow-up period of 35 days. The possible relationship of organ invasion by C. albicans and skin candidosis is discussed. Des cobayes Albinos, non prétraités ont été infectés par voie intraveineuse par Candida albicans. Une eruption cutanée en résulte avec invasion (pseudo-)mycélienne du poil et de la couche kératinisée de l'épiderme. L'évolution des lésions est suivie au moyen de cultures et par examen histopathologique des organes, pendant une période expérimentale de 35 jours. La relation possible entre une candidose cutanée et l'atteinte primaire d'organes internes par Candida albicans est discutée.This publication has 18 references indexed in Scilit:
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